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2005). These effects were not shocking if we contemplate that PEA is a improperly drinking water‐soluble compound, which might Restrict its oral absorption and bioavailability, but they may also propose a short‐lived action of PEA, in settlement with the fact that this compound is degraded by two diverse hydrolases, which is, NAAA and FAAH. Aft
Key phrases: fibromyalgia; palmitoylethanolamide; melatonin; nutraceuticals; agony; rest; quality of lifeThe anti‐inflammatory outcomes of PEA appear to be generally related to its capacity to modulate mast cell activation and degranulation, and this motion is generally known as the ALIA (autacoid local inflammation antagonism) mechanism (Aloe et